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Female Bias in Rhox6 and 9 Regulation by the Histone Demethylase KDM6A

The Rhox cluster on the mouse X chromosome contains reproduction-related homeobox genes expressed in a sexually dimorphic manner. We report that two members of the Rhox cluster, Rhox6 and 9, are regulated by de-methylation of histone H3 at lysine 27 by KDM6A, a histone demethylase with female-biased...

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Detalles Bibliográficos
Autores principales: Berletch, Joel B., Deng, Xinxian, Nguyen, Di Kim, Disteche, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642083/
https://www.ncbi.nlm.nih.gov/pubmed/23658530
http://dx.doi.org/10.1371/journal.pgen.1003489