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MAP kinases bind endothelial nitric oxide synthase
Endothelial nitric oxide synthase (eNOS) contains a motif similar to recognition sequences in known MAPK binding partners. In optical biosensing experiments, eNOS bound p38 and ERK with ∼100 nM affinity and complex kinetics. Binding is diffusion-limited (k(on) ∼ .15 × 10(6) M(−1) s(−1)). Neuronal NO...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642102/ https://www.ncbi.nlm.nih.gov/pubmed/23650581 http://dx.doi.org/10.1016/j.fob.2012.02.002 |