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MAP kinases bind endothelial nitric oxide synthase

Endothelial nitric oxide synthase (eNOS) contains a motif similar to recognition sequences in known MAPK binding partners. In optical biosensing experiments, eNOS bound p38 and ERK with ∼100 nM affinity and complex kinetics. Binding is diffusion-limited (k(on) ∼ .15 × 10(6) M(−1) s(−1)). Neuronal NO...

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Detalles Bibliográficos
Autores principales:	Chrestensen, Carol A., McMurry, Jonathan L., Salerno, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642102/ https://www.ncbi.nlm.nih.gov/pubmed/23650581 http://dx.doi.org/10.1016/j.fob.2012.02.002

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