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Modification of Histone Acetylation Facilitates Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells
The multi-potentiality of mesenchymal stem cells makes them excellent options for future tissue engineering and clinical therapy, including liver injury. In this study, we investigated the effects of valproic acid (VPA), a direct inhibitor of histone deacetylase (HDAC), on the hepatic differentiatio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642107/ https://www.ncbi.nlm.nih.gov/pubmed/23658825 http://dx.doi.org/10.1371/journal.pone.0063405 |