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The Hsp90 inhibitor 17-AAG represses calcium-induced cytokeratin 1 and 10 expression in HaCaT keratinocytes
Hsp90 is essential for maintaining the activity of numerous signaling factors, and plays a key role in cellular signal transduction networks. 17-Allylamino-17-demethoxygeldanamycin (17-AAG) is an ansamycin antibiotic that binds to Hsp90 and inhibits its function. HaCaT human keratinocytes were used...
Autores principales: | Miyoshi, Sadanori, Yamazaki, Shota, Uchiumi, Asato, Katagata, Yohtaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642114/ https://www.ncbi.nlm.nih.gov/pubmed/23650580 http://dx.doi.org/10.1016/j.fob.2012.03.002 |
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