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Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells
Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants lacking the carboxy-terminal region in CRPC may lead to therapy inefficacy. These AR variants are s...
Autores principales: | Cottard, Félicie, Asmane, Irène, Erdmann, Eva, Bergerat, Jean-Pierre, Kurtz, Jean-Emmanuel, Céraline, Jocelyn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642121/ https://www.ncbi.nlm.nih.gov/pubmed/23658830 http://dx.doi.org/10.1371/journal.pone.0063466 |
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