Dihydroartemisinin induces autophagy and inhibits the growth of iron-loaded human myeloid leukemia K562 cells via ROS toxicity

Dihydroartemisinin (DHA), an active metabolite of artemisinin derivatives, is the most remarkable anti-malarial drug and has little toxicity to humans. Recent studies have shown that DHA effectively inhibits the growth of cancer cells. In the present study, we intended to elucidate the mechanisms un...

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Detalles Bibliográficos
Autores principales: Wang, Zeng, Hu, Wei, Zhang, Jia-Li, Wu, Xiu-Hua, Zhou, Hui-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642128/
https://www.ncbi.nlm.nih.gov/pubmed/23650588
http://dx.doi.org/10.1016/j.fob.2012.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642128/
https://www.ncbi.nlm.nih.gov/pubmed/23650588
http://dx.doi.org/10.1016/j.fob.2012.05.002

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