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Calmodulin Adopts an Extended Conformation when Interacting with L-Selectin in Membranes
Calmodulin, an intracellular calcium-binding protein, is thought to regulate ectodomain shedding of many membrane proteins, but the underlying molecular mechanism has remained unclear. Basing on a solution structure of calcium-loaded calmodulin in complex with a L-selectin fragment that contains a p...
Autores principales: | Deng, Wei, Putkey, John A., Li, Renhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642142/ https://www.ncbi.nlm.nih.gov/pubmed/23658780 http://dx.doi.org/10.1371/journal.pone.0062861 |
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