CD248 expression on mesenchymal stromal cells is required for post-natal and infection-dependent thymus remodelling and regeneration

The role of mesenchymal stromal cells (MSCs) in regulating immune responses in the thymus is currently unclear. Here we report the existence and role of a MSC population in the thymus that expresses the pericyte and MSC marker CD248 (endosialin). We show using a CD248-deficient mouse model, that CD2...

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Detalles Bibliográficos
Autores principales: Lax, Siân, Ross, Ewan A., White, Andrea, Marshall, Jennifer L., Jenkinson, William E., Isacke, Clare M., Huso, David L., Cunningham, Adam F., Anderson, Graham, Buckley, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642154/
https://www.ncbi.nlm.nih.gov/pubmed/23650598
http://dx.doi.org/10.1016/j.fob.2012.07.003

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