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Antimalarial drug chloroquine counteracts activation of indoleamine (2,3)-dioxygenase activity in human PBMC

Antimalarial chloroquine is also used for the treatment of immune-mediated diseases. The interference of chloroquine with interferon-γ-induced tryptophan breakdown and neopterin production has been investigated in human peripheral blood mononuclear cells (PBMC) in vitro. Micromolar concentrations (2...

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Detalles Bibliográficos
Autores principales:	Gostner, Johanna M., Schröcksnadel, Sebastian, Becker, Kathrin, Jenny, Marcel, Schennach, Harald, Überall, Florian, Fuchs, Dietmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642164/ https://www.ncbi.nlm.nih.gov/pubmed/23650606 http://dx.doi.org/10.1016/j.fob.2012.08.004

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