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Characterization of Acid Sphingomyelinase Activity in Human Cerebrospinal Fluid

BACKGROUND: As a key enzyme in sphingolipid metabolism, acid sphingomyelinase (ASM) is involved in the regulation of cell fate and signaling via hydrolysis of sphingomyelin to form ceramide. While increased activity of the lysosomal form has been associated with various pathological conditions, ther...

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Detalles Bibliográficos
Autores principales:	Mühle, Christiane, Huttner, Hagen B., Walter, Silke, Reichel, Martin, Canneva, Fabio, Lewczuk, Piotr, Gulbins, Erich, Kornhuber, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642176/ https://www.ncbi.nlm.nih.gov/pubmed/23658784 http://dx.doi.org/10.1371/journal.pone.0062912

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