Cargando…
A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei
A-type lamins encoded by LMNA form a structural fibrillar meshwork within the mammalian nucleus. How this nuclear organization may influence the execution of biological processes involving DNA transactions remains unclear. Here, we characterize changes in the dynamics and biochemical interactions of...
Autores principales: | Mahen, Robert, Hattori, Hiroyoshi, Lee, Miyoung, Sharma, Pooja, Jeyasekharan, Anand D., Venkitaraman, Ashok R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642183/ https://www.ncbi.nlm.nih.gov/pubmed/23658700 http://dx.doi.org/10.1371/journal.pone.0061893 |
Ejemplares similares
-
The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry
por: Ayoub, Nabieh, et al.
Publicado: (2009) -
Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance
por: Lee, Miyoung, et al.
Publicado: (2021) -
A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization
por: Jeyasekharan, Anand D, et al.
Publicado: (2013) -
p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response
por: Hattori, Hiroyoshi, et al.
Publicado: (2014) -
Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP
por: Wickramasinghe, Vihandha O., et al.
Publicado: (2014)