Insight to neoplastic thyroid lesions by fine needle aspiration cytology
BACKGROUND: Fine needle aspiration cytology (FNAC) is a valuable adjunct to pre-operative screening in the diagnosis of thyroid nodules, and in most cases, it can distinguish between benign and malignant lesions. AIM: To study the cytology of neoplastic thyroid lesions to minimize surgical intervent...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643357/ https://www.ncbi.nlm.nih.gov/pubmed/23661936 http://dx.doi.org/10.4103/0970-9371.107508 |
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author | Rangaswamy, M Narendra, KL Patel, S Gururajprasad, C Manjunath, GV |
author_facet | Rangaswamy, M Narendra, KL Patel, S Gururajprasad, C Manjunath, GV |
author_sort | Rangaswamy, M |
collection | PubMed |
description | BACKGROUND: Fine needle aspiration cytology (FNAC) is a valuable adjunct to pre-operative screening in the diagnosis of thyroid nodules, and in most cases, it can distinguish between benign and malignant lesions. AIM: To study the cytology of neoplastic thyroid lesions to minimize surgical intervention and for confirmation of the diagnosis by histopathological study. MATERIALS AND METHODS: 100 cases of thyroid FNAC smears were analyzed and cyto-histopathological correlation was done in 47 cases. Galen and Gambino's method was used to calculate the sensitivity and positive predictive value. RESULTS: Of the 100 cases, 90 were diagnosed as neoplastic lesions by FNAC and ten cases as non-neoplastic lesions, which turned out to be neoplasms on histopathological study. Among 100 cases, 47 were biopsied and subjected to histopathological study. The sensitivity of FNAC was 75.60%, and positive predictive value was 83.78% for malignant lesions. CONCLUSIONS: FNAC is a rapid, efficient, cost-effective, relatively painless procedure with a high diagnostic accuracy. It has high rate of sensitivity and positive predictive value in diagnosing thyroid neoplastic lesions. Hence, it is a valuable tool in the diagnosis and management of patients. |
format | Online Article Text |
id | pubmed-3643357 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36433572013-05-09 Insight to neoplastic thyroid lesions by fine needle aspiration cytology Rangaswamy, M Narendra, KL Patel, S Gururajprasad, C Manjunath, GV J Cytol Original Article BACKGROUND: Fine needle aspiration cytology (FNAC) is a valuable adjunct to pre-operative screening in the diagnosis of thyroid nodules, and in most cases, it can distinguish between benign and malignant lesions. AIM: To study the cytology of neoplastic thyroid lesions to minimize surgical intervention and for confirmation of the diagnosis by histopathological study. MATERIALS AND METHODS: 100 cases of thyroid FNAC smears were analyzed and cyto-histopathological correlation was done in 47 cases. Galen and Gambino's method was used to calculate the sensitivity and positive predictive value. RESULTS: Of the 100 cases, 90 were diagnosed as neoplastic lesions by FNAC and ten cases as non-neoplastic lesions, which turned out to be neoplasms on histopathological study. Among 100 cases, 47 were biopsied and subjected to histopathological study. The sensitivity of FNAC was 75.60%, and positive predictive value was 83.78% for malignant lesions. CONCLUSIONS: FNAC is a rapid, efficient, cost-effective, relatively painless procedure with a high diagnostic accuracy. It has high rate of sensitivity and positive predictive value in diagnosing thyroid neoplastic lesions. Hence, it is a valuable tool in the diagnosis and management of patients. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3643357/ /pubmed/23661936 http://dx.doi.org/10.4103/0970-9371.107508 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Rangaswamy, M Narendra, KL Patel, S Gururajprasad, C Manjunath, GV Insight to neoplastic thyroid lesions by fine needle aspiration cytology |
title | Insight to neoplastic thyroid lesions by fine needle aspiration cytology |
title_full | Insight to neoplastic thyroid lesions by fine needle aspiration cytology |
title_fullStr | Insight to neoplastic thyroid lesions by fine needle aspiration cytology |
title_full_unstemmed | Insight to neoplastic thyroid lesions by fine needle aspiration cytology |
title_short | Insight to neoplastic thyroid lesions by fine needle aspiration cytology |
title_sort | insight to neoplastic thyroid lesions by fine needle aspiration cytology |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643357/ https://www.ncbi.nlm.nih.gov/pubmed/23661936 http://dx.doi.org/10.4103/0970-9371.107508 |
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