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All three RNA recognition motifs and the hinge region of HuC play distinct roles in the regulation of alternative splicing
The four Hu [embryonic lethal abnormal vision-like (ELAVL)] protein family members regulate alternative splicing by binding to U-rich sequences surrounding target exons and affecting the interaction of the splicing machinery and/or local chromatin modifications. Each of the Hu proteins contains a di...
Autores principales: | Hinman, Melissa N., Zhou, Hua-Lin, Sharma, Alok, Lou, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643579/ https://www.ncbi.nlm.nih.gov/pubmed/23525460 http://dx.doi.org/10.1093/nar/gkt166 |
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