Distinctive contributions of the ribosomal P-site elements m(2)G966, m(5)C967 and the C-terminal tail of the S9 protein in the fidelity of initiation of translation in Escherichia coli

The accuracy of pairing of the anticodon of the initiator tRNA (tRNA(fMet)) and the initiation codon of an mRNA, in the ribosomal P-site, is crucial for determining the translational reading frame. However, a direct role of any ribosomal element(s) in scrutinizing this pairing is unknown. The P-site...

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Detalles Bibliográficos
Autores principales: Arora, Smriti, Bhamidimarri, Satya Prathyusha, Bhattacharyya, Moitrayee, Govindan, Ashwin, Weber, Michael H. W., Vishveshwara, Saraswathi, Varshney, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643588/
https://www.ncbi.nlm.nih.gov/pubmed/23530111
http://dx.doi.org/10.1093/nar/gkt175

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