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High-throughput identification of long-range regulatory elements and their target promoters in the human genome

Enhancer elements are essential for tissue-specific gene regulation during mammalian development. Although these regulatory elements are often distant from their target genes, they affect gene expression by recruiting transcription factors to specific promoter regions. Because of this long-range act...

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Detalles Bibliográficos
Autores principales: Hwang, Yih-Chii, Zheng, Qi, Gregory, Brian D., Wang, Li-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643598/
https://www.ncbi.nlm.nih.gov/pubmed/23525463
http://dx.doi.org/10.1093/nar/gkt188