Reconstitution of recombination-associated DNA synthesis with human proteins

The repair of DNA breaks by homologous recombination is a high-fidelity process, necessary for the maintenance of genome integrity. Thus, DNA synthesis associated with recombinational repair must be largely error-free. In this report, we show that human DNA polymerase delta (δ) is capable of robust...

Descripción completa

Detalles Bibliográficos
Autores principales: Sneeden, Jessica L., Grossi, Sara M., Tappin, Inger, Hurwitz, Jerard, Heyer, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643601/
https://www.ncbi.nlm.nih.gov/pubmed/23535143
http://dx.doi.org/10.1093/nar/gkt192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643601/
https://www.ncbi.nlm.nih.gov/pubmed/23535143
http://dx.doi.org/10.1093/nar/gkt192

Ejemplares similares