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Biological interactions of CYP2C19 genotypes with CYP3A4*18, CYP3A5*3, and MDR1-3435 in living donor liver transplantation recipients
BACKGROUND: Polymorphisms in CYP2C19 are related to the metabolic oxidation of drugs to varying degrees. The CYP3A4*18, CYP3A5*3, and MDR1-3435 variant alleles are very important, particularly in tacrolimus metabolism in organ transplant rejection. AIM: The aim of this study is o explore possible in...
Autores principales: | Chiu, King-Wah, Hu, Tsung-Hui, Nakano, Toshiaki, Chen, Kuang-Den, Lai, Chia-Yun, Hsu, Li-Wen, Tseng, Hui-Peng, Chiu, Ho-Ching, Cheng, Yu-Fan, Goto, Shigeru, Chen, Chao-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643843/ https://www.ncbi.nlm.nih.gov/pubmed/23617933 http://dx.doi.org/10.1186/2047-1440-2-6 |
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