A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation

BACKGROUND: Metabolic syndrome (MetS) is an aberration associated with increased risk for cancer and inflammation. Adiponectin, an adipocyte-produced abundant protein hormone, has countering effect on the diabetogenic and atherogenic components of MetS. Plasma levels of adiponectin are negatively co...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Kent, Jack W, Olivier, Michael, Ali, Omar, Cerjak, Diana, Broeckel, Ulrich, Abdou, Reham M, Dyer, Thomas D, Comuzzie, Anthony, Curran, Joanne E, Carless, Melanie A, Rainwater, David L, Göring, Harald H H, Blangero, John, Kissebah, Ahmed H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643849/
https://www.ncbi.nlm.nih.gov/pubmed/23628382
http://dx.doi.org/10.1186/1755-8794-6-14

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