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A model of HIV drug resistance driven by heterogeneities in host immunity and adherence patterns

BACKGROUND: Population transmission models of antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) use simplistic assumptions – typically constant, homogeneous rates – to represent the short-term risk and long-term effects of drug resistance. In contrast, within-host models of drug resis...

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Detalles Bibliográficos
Autores principales: Bershteyn, Anna, Eckhoff, Philip A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643872/
https://www.ncbi.nlm.nih.gov/pubmed/23379669
http://dx.doi.org/10.1186/1752-0509-7-11