Cargando…
Downregulation of OPA3 Is Responsible for Transforming Growth Factor-β-Induced Mitochondrial Elongation and F-Actin Rearrangement in Retinal Pigment Epithelial ARPE-19 Cells
Transforming growth factor-β signaling is known to be a key signaling pathway in the induction of epithelial–mesenchymal transition. However, the mechanism of TGF-β signaling in the modulation of EMT remains unclear. In this study, we found that TGF-β treatment resulted in elongation of mitochondria...
Autores principales: | Ryu, Seung-Wook, Yoon, Jonghee, Yim, Nambin, Choi, Kyungsun, Choi, Chulhee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643898/ https://www.ncbi.nlm.nih.gov/pubmed/23658835 http://dx.doi.org/10.1371/journal.pone.0063495 |
Ejemplares similares
-
Mutant Ubiquitin UBB+1 Induces Mitochondrial Fusion by Destabilizing Mitochondrial Fission-Specific Proteins and Confers Resistance to Oxidative Stress-Induced Cell Death in Astrocytic Cells
por: Yim, Nambin, et al.
Publicado: (2014) -
Pirfenidone inhibits transforming growth factor-β1-induced fibrogenesis by blocking nuclear translocation of Smads in human retinal pigment epithelial cell line ARPE-19
por: Choi, Kyungsun, et al.
Publicado: (2012) -
The Mitochondrial Fusion-Related Proteins Mfn2 and OPA1 are Transcriptionally Induced during Differentiation of Bone Marrow Progenitors to Immature Dendritic Cells
por: Ryu, Seung-Wook, et al.
Publicado: (2015) -
Extracellular vesicles as novel carriers for therapeutic molecules
por: Yim, Nambin, et al.
Publicado: (2016) -
Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
por: Yim, Nambin, et al.
Publicado: (2016)