Endoplasmic Reticulum Stress–Induced Resistance to Doxorubicin Is Reversed by Paeonol Treatment in Human Hepatocellular Carcinoma Cells

BACKGROUND: Endoplasmic reticulum stress (ER stress) is generally activated in solid tumors and results in tumor cell anti-apoptosis and drug resistance. Paeonol (Pae, 2-hydroxy-4-methoxyacetophenone), is a natural product extracted from the root of Paeonia Suffruticosa Andrew. Although Pae displays...

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Detalles Bibliográficos
Autores principales: Fan, Lulu, Song, Bing, Sun, Guoping, Ma, Tai, Zhong, Fei, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643935/
https://www.ncbi.nlm.nih.gov/pubmed/23658755
http://dx.doi.org/10.1371/journal.pone.0062627

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