VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Vascular endothelial growth factor (VEGF) guides the path of new vessel sprouts by inducing VEGF receptor-2 activity in the sprout tip. In the stalk cells of the sprout, VEGF receptor-2 activity is downregulated. Here, we show that VEGF receptor-2 in stalk cells is dephosphorylated by the endotheliu...

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Detalles Bibliográficos
Autores principales: Hayashi, Makoto, Majumdar, Arindam, Li, Xiujuan, Adler, Jeremy, Sun, Zuyue, Vertuani, Simona, Hellberg, Carina, Mellberg, Sofie, Koch, Sina, Dimberg, Anna, Young Koh, Gou, Dejana, Elisabetta, Belting, Heinz-Georg, Affolter, Markus, Thurston, Gavin, Holmgren, Lars, Vestweber, Dietmar, Claesson-Welsh, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644080/
https://www.ncbi.nlm.nih.gov/pubmed/23575676
http://dx.doi.org/10.1038/ncomms2683

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