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Comparison of automated and manual FISH for evaluation of HER2 gene status on breast carcinoma core biopsies

BACKGROUND: Positive HER2 status identifies breast carcinomas that might respond to trastuzumab treatment. Manual HER2 fluorescent in situ hybridisation (FISH) is the most readily used method to detect HER2 gene amplification which defines positive HER2 status in addition to HER2 protein overexpress...

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Detalles Bibliográficos
Autores principales: Öhlschlegel, Christian, Kradolfer, Doris, Hell, Margreth, Jochum, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644269/
https://www.ncbi.nlm.nih.gov/pubmed/23601823
http://dx.doi.org/10.1186/1472-6890-13-13