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Notch4 is required for tumor onset and perfusion

BACKGROUND: Notch4 is a member of the Notch family of receptors that is primarily expressed in the vascular endothelial cells. Genetic deletion of Notch4 does not result in an overt phenotype in mice, thus the function of Notch4 remains poorly understood. METHODS: We examined the requirement for Not...

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Detalles Bibliográficos
Autores principales:	Costa, Maria José, Wu, Xiaoqing, Cuervo, Henar, Srinivasan, Ruchika, Bechis, Seth K, Cheang, Ellen, Marjanovic, Olivera, Gridley, Thomas, Cvetic, Christin A, Wang, Rong A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644271/ https://www.ncbi.nlm.nih.gov/pubmed/23601498 http://dx.doi.org/10.1186/2045-824X-5-7

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