Snail2 promotes osteosarcoma cell motility through remodelling of the actin cytoskeleton and regulates tumor development

The function of Snail2 in mesenchymal tumors is, to date unknown. Using knockdown and overexpression studies, we show that Snail2 regulates migration and invasion of osteosarcoma cells. Knockdown resulted in significantly decreased motility, remodelling of the actin cytoskeleton, and loss of cellula...

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Detalles Bibliográficos
Autores principales: Sharili, Amir-Shaya, Allen, Steve, Smith, Ken, Price, Joanna, McGonnell, Imelda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644682/
https://www.ncbi.nlm.nih.gov/pubmed/23352643
http://dx.doi.org/10.1016/j.canlet.2013.01.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644682/
https://www.ncbi.nlm.nih.gov/pubmed/23352643
http://dx.doi.org/10.1016/j.canlet.2013.01.027

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