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The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats

OBJECTIVE: Cisplatin is a widely used chemotherapeutic agent in the treatment of cancers in clinic; but it often induces adverse effects on ovarian functions such as reduced fertility and premature menopause. Mesna could attenuate the cisplatin-induced ovarian damages; however, the underlying mechan...

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Detalles Bibliográficos
Autores principales: Li, Xiaohuan, Yang, Shu, Lv, Xiangyang, Sun, Haimei, Weng, Jing, Liang, Yuanjing, Zhou, Deshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644695/
https://www.ncbi.nlm.nih.gov/pubmed/23653836
http://dx.doi.org/10.3802/jgo.2013.24.2.177