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Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells

The zwitterionic capsular polysaccharide A (PSA) of Bacteroides fragilis is the first carbohydrate antigen described to be presented in major histocompatibility complex (MHC) class II for the induction of CD4(+) T cell responses. However, the identity of the receptor mediating binding and internaliz...

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Detalles Bibliográficos
Autores principales: Bloem, Karien, García-Vallejo, Juan J., Vuist, Ilona M., Cobb, Brian A., van Vliet, Sandra J., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644800/
https://www.ncbi.nlm.nih.gov/pubmed/23653626
http://dx.doi.org/10.3389/fimmu.2013.00103