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Diacylglycerol Kinases: Regulated Controllers of T Cell Activation, Function, and Development

Diacylglycerol kinases (DGKs) are a diverse family of enzymes that catalyze the conversion of diacylglycerol (DAG), a crucial second messenger of receptor-mediated signaling, to phosphatidic acid (PA). Both DAG and PA are bioactive molecules that regulate a wide set of intracellular signaling protei...

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Detalles Bibliográficos
Autores principales: Joshi, Rohan P., Koretzky, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645659/
https://www.ncbi.nlm.nih.gov/pubmed/23531532
http://dx.doi.org/10.3390/ijms14046649