Protein Tyrosine Nitration and Thiol Oxidation by Peroxynitrite—Strategies to Prevent These Oxidative Modifications

The reaction product of nitric oxide and superoxide, peroxynitrite, is a potent biological oxidant. The most important oxidative protein modifications described for peroxynitrite are cysteine-thiol oxidation and tyrosine nitration. We have previously demonstrated that intrinsic heme-thiolate (P450)-...

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Detalles Bibliográficos
Autores principales: Daiber, Andreas, Daub, Steffen, Bachschmid, Markus, Schildknecht, Stefan, Oelze, Matthias, Steven, Sebastian, Schmidt, Patrick, Megner, Alexandra, Wada, Masayuki, Tanabe, Tadashi, Münzel, Thomas, Bottari, Serge, Ullrich, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645702/
https://www.ncbi.nlm.nih.gov/pubmed/23567270
http://dx.doi.org/10.3390/ijms14047542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645702/
https://www.ncbi.nlm.nih.gov/pubmed/23567270
http://dx.doi.org/10.3390/ijms14047542

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