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Development of a Preclinical Therapeutic Model of Human Brain Metastasis with Chemoradiotherapy

Currently, survival of breast cancer patients with brain metastasis ranges from 2 to 16 months. In experimental brain metastasis studies, only 10% of lesions with the highest permeability exhibited cytotoxic responses to paclitaxel or doxorubicin. Therefore, radiation is the most frequently used tre...

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Detalles Bibliográficos
Autores principales: Martínez-Aranda, Antonio, Hernández, Vanessa, Picón, Cristina, Modolell, Ignasi, Sierra, Angels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645744/
https://www.ncbi.nlm.nih.gov/pubmed/23591844
http://dx.doi.org/10.3390/ijms14048306