Acute Phase CD8+ T Lymphocytes against Alternate Reading Frame Epitopes Select for Rapid Viral Escape during SIV Infection

CD8+ T Lymphocytes (CTL) can control AIDS virus replication. However, natural selection favoring viral variants that escape CTL recognition is a common feature of both simian immunodeficiency virus (SIV) infection of macaques and HIV infection of humans. Emerging data indicate that CTL directed agai...

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Detalles Bibliográficos
Autores principales: Walsh, Andrew D., Bimber, Benjamin N., Das, Arpita, Piaskowski, Shari M., Rakasz, Eva G., Bean, Alexander T., Mudd, Philip A., Ericsen, Adam J., Wilson, Nancy A., Hughes, Austin L., O'Connor, David H., Maness, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645990/
https://www.ncbi.nlm.nih.gov/pubmed/23671565
http://dx.doi.org/10.1371/journal.pone.0061383

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