Large-Scale Modelling of the Divergent Spectrin Repeats in Nesprins: Giant Modular Proteins

Nesprin-1 and nesprin-2 are nuclear envelope (NE) proteins characterized by a common structure of an SR (spectrin repeat) rod domain and a C-terminal transmembrane KASH [Klarsicht–ANC–Syne-homology] domain and display N-terminal actin-binding CH (calponin homology) domains. Mutations in these protei...

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Detalles Bibliográficos
Autores principales: Autore, Flavia, Pfuhl, Mark, Quan, Xueping, Williams, Aisling, Roberts, Roland G., Shanahan, Catherine M., Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646009/
https://www.ncbi.nlm.nih.gov/pubmed/23671687
http://dx.doi.org/10.1371/journal.pone.0063633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646009/
https://www.ncbi.nlm.nih.gov/pubmed/23671687
http://dx.doi.org/10.1371/journal.pone.0063633

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