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When are the BET factors the most sensitive to bromodomain inhibitors?
The recent publication of two detailed studies of mouse spermatogenesis, either after chemical inhibition of the BET bromodomains, or in the context of genetic alterations of one specific BET member, Brdt, provides the unique opportunity to assess the functional impact of BET bromodomain inhibitors.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646053/ https://www.ncbi.nlm.nih.gov/pubmed/23412362 http://dx.doi.org/10.4161/trns.23191 |
| _version_ | 1782268563454689280 |
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| author | Khochbin, Saadi |
| author_facet | Khochbin, Saadi |
| author_sort | Khochbin, Saadi |
| collection | PubMed |
| description | The recent publication of two detailed studies of mouse spermatogenesis, either after chemical inhibition of the BET bromodomains, or in the context of genetic alterations of one specific BET member, Brdt, provides the unique opportunity to assess the functional impact of BET bromodomain inhibitors. |
| format | Online Article Text |
| id | pubmed-3646053 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-36460532013-06-03 When are the BET factors the most sensitive to bromodomain inhibitors? Khochbin, Saadi Transcription Point of View The recent publication of two detailed studies of mouse spermatogenesis, either after chemical inhibition of the BET bromodomains, or in the context of genetic alterations of one specific BET member, Brdt, provides the unique opportunity to assess the functional impact of BET bromodomain inhibitors. Landes Bioscience 2013-03-01 2013-02-14 /pmc/articles/PMC3646053/ /pubmed/23412362 http://dx.doi.org/10.4161/trns.23191 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Point of View Khochbin, Saadi When are the BET factors the most sensitive to bromodomain inhibitors? |
| title | When are the BET factors the most sensitive to bromodomain inhibitors? |
| title_full | When are the BET factors the most sensitive to bromodomain inhibitors? |
| title_fullStr | When are the BET factors the most sensitive to bromodomain inhibitors? |
| title_full_unstemmed | When are the BET factors the most sensitive to bromodomain inhibitors? |
| title_short | When are the BET factors the most sensitive to bromodomain inhibitors? |
| title_sort | when are the bet factors the most sensitive to bromodomain inhibitors? |
| topic | Point of View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646053/ https://www.ncbi.nlm.nih.gov/pubmed/23412362 http://dx.doi.org/10.4161/trns.23191 |
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