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HIF proteins connect the RB-E2F factors to angiogenesis
Recently, we showed that E2F7 and E2F8 (E2F7/8) are critical regulators of angiogenesis through transcriptional control of VEGFA in cooperation with HIF.(1) Here we investigate the existence of other novel putative angiogenic E2F7/8-HIF targets, and discuss the role of the RB-E2F pathway in regulati...
Autores principales: | Bakker, Walbert. J., Weijts, Bart G.M.W., Westendorp, Bart, de Bruin, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646055/ https://www.ncbi.nlm.nih.gov/pubmed/23412359 http://dx.doi.org/10.4161/trns.23680 |
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