N-ras Mutation Detection by Pyrosequencing in Adult Patients with Acute Myeloid Leukemia at a Single Institution

BACKGROUND: N-ras mutations are one of the most commonly detected abnormalities of myeloid origin. N-ras mutations result in a constitutively active N-ras protein that induces uncontrolled cell proliferation and inhibits apoptosis. We analyzed N-ras mutations in adult patients with AML at a particul...

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Detalles Bibliográficos
Autores principales: Jeong, Ji Hun, Park, Soon Ho, Park, Mi Jung, Kim, Moon Jin, Kim, Kyung Hee, Park, Pil Whan, Seo, Yiel Hea, Lee, Jae Hoon, Park, Jinny, Hong, Junshik, Ahn, Jeong Yeal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646189/
https://www.ncbi.nlm.nih.gov/pubmed/23667841
http://dx.doi.org/10.3343/alm.2013.33.3.159

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