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Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms

The mammalian P2X7 receptors (P2X7Rs), a member of the ionotropic P2X receptor family with distinctive functional properties, play an important part in mediating extracellular ATP signaling in health and disease. A clear delineation of the molecular mechanisms underlying the key receptor properties,...

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Detalles Bibliográficos
Autores principales:	Jiang, Lin-Hua, Baldwin, Jocelyn M., Roger, Sebastien, Baldwin, Stephen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646254/ https://www.ncbi.nlm.nih.gov/pubmed/23675347 http://dx.doi.org/10.3389/fphar.2013.00055

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