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Kinetic and thermodynamic analysis of the conformational folding process of SS-reduced bovine pancreatic ribonuclease A using a selenoxide reagent with high oxidizing ability

Redox-coupled folding pathways of bovine pancreatic ribonuclease A (RNase A) with four intramolecular disulfide (SS) bonds comprise three phases: (I) SS formation to generate partially oxidized intermediate ensembles with no rigid folded structure; (II) SS rearrangement from the three SS intermediat...

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Detalles Bibliográficos
Autores principales:	Arai, Kenta, Kumakura, Fumio, Iwaoka, Michio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646284/ https://www.ncbi.nlm.nih.gov/pubmed/23653890 http://dx.doi.org/10.1016/j.fob.2012.04.001

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