Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization

Alzheimer’s disease is the leading cause of dementia in the elderly. Pathologically it is characterized by the presence of amyloid plaques and neuronal loss within the brain tissue of affected individuals. It is now widely hypothesised that fibrillar structures represent an inert structure. Biophysi...

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Detalles Bibliográficos
Autores principales: Ryan, Timothy M., Caine, Joanne, Mertens, Haydyn D.T., Kirby, Nigel, Nigro, Julie, Breheney, Kerry, Waddington, Lynne J., Streltsov, Victor A., Curtain, Cyril, Masters, Colin L., Roberts, Blaine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646356/
https://www.ncbi.nlm.nih.gov/pubmed/23678397
http://dx.doi.org/10.7717/peerj.73

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