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Global Quantitative SILAC Phosphoproteomics Reveals Differential Phosphorylation Is Widespread between the Procyclic and Bloodstream Form Lifecycle Stages of Trypanosoma brucei

[Image: see text] We report a global quantitative phosphoproteomic study of bloodstream and procyclic form Trypanosoma brucei using SILAC labeling of each lifecycle stage. Phosphopeptide enrichment by SCX and TiO(2) led to the identification of a total of 10096 phosphorylation sites on 2551 protein...

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Detalles Bibliográficos
Autores principales: Urbaniak, Michael D., Martin, David M. A., Ferguson, Michael A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646404/
https://www.ncbi.nlm.nih.gov/pubmed/23485197
http://dx.doi.org/10.1021/pr400086y