In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation

Numerous studies have described the altered expression and the causal role of microRNAs (miRNAs) in human cancer. However, to date, efforts to modulate miRNA levels for therapeutic purposes have been challenging to implement. Here we find that nucleolin (NCL), a major nucleolar protein, posttranscri...

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Detalles Bibliográficos
Autores principales: Pichiorri, Flavia, Palmieri, Dario, De Luca, Luciana, Consiglio, Jessica, You, Jia, Rocci, Alberto, Talabere, Tiffany, Piovan, Claudia, Lagana, Alessandro, Cascione, Luciano, Guan, Jingwen, Gasparini, Pierluigi, Balatti, Veronica, Nuovo, Gerard, Coppola, Vincenzo, Hofmeister, Craig C., Marcucci, Guido, Byrd, John C., Volinia, Stefano, Shapiro, Charles L., Freitas, Michael A., Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646490/
https://www.ncbi.nlm.nih.gov/pubmed/23610125
http://dx.doi.org/10.1084/jem.20120950

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