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Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3(+) dendritic cells at cross presentation
Human BDCA3(+) dendritic cells (DCs), the proposed equivalent to mouse CD8α(+) DCs, are widely thought to cross present antigens on MHC class I (MHCI) molecules more efficiently than other DC populations. If true, it is unclear whether this reflects specialization for cross presentation or a general...
Autores principales: | Cohn, Lillian, Chatterjee, Bithi, Esselborn, Filipp, Smed-Sörensen, Anna, Nakamura, Norihiro, Chalouni, Cécile, Lee, Byoung-Chul, Vandlen, Richard, Keler, Tibor, Lauer, Peter, Brockstedt, Dirk, Mellman, Ira, Delamarre, Lélia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646496/ https://www.ncbi.nlm.nih.gov/pubmed/23569326 http://dx.doi.org/10.1084/jem.20121251 |
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