MHC II tetramers visualize human CD4(+) T cell responses to Epstein–Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response

Virus-specific CD4(+) T cells are key orchestrators of host responses to viral infection yet, compared with their CD8(+) T cell counterparts, remain poorly characterized at the single cell level. Here we use nine MHC II–epitope peptide tetramers to visualize human CD4(+) T cell responses to Epstein–...

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Detalles Bibliográficos
Autores principales: Long, Heather M., Chagoury, Odette L., Leese, Alison M., Ryan, Gordon B., James, Eddie, Morton, Laura T., Abbott, Rachel J.M., Sabbah, Shereen, Kwok, William, Rickinson, Alan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646497/
https://www.ncbi.nlm.nih.gov/pubmed/23569328
http://dx.doi.org/10.1084/jem.20121437

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