The link between antibodies to OxLDL and natural protection against pneumococci depends on D(H) gene conservation

Selection and physiological production of protective natural antibodies (NAbs) have been associated with exposure to endogenous antigens. The extent to which this association depends on germline NAb sequence is uncertain. Here we show that alterations in germline D(H) sequence can sever the associat...

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Detalles Bibliográficos
Autores principales: Vale, Andre M., Kapoor, Pratibha, Skibinski, Greg A., Elgavish, Ada, Mahmoud, Tamer I., Zemlin, Cosima, Zemlin, Michael, Burrows, Peter D., Nobrega, Alberto, Kearney, John F., Briles, David E., Schroeder, Harry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646500/
https://www.ncbi.nlm.nih.gov/pubmed/23589567
http://dx.doi.org/10.1084/jem.20121861

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