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MPN patients harbor recurrent truncating mutations in transcription factor NF-E2

The molecular etiology of myeloproliferative neoplasms (MPNs) remains incompletely understood, despite recent advances incurred through the discovery of several different mutations in MPN patients. We have recently described overexpression of the transcription factor NF-E2 in MPN patients and shown...

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Detalles Bibliográficos
Autores principales: Jutzi, Jonas S., Bogeska, Ruzhica, Nikoloski, Gorica, Schmid, Corina A., Seeger, Thalia S., Stegelmann, Frank, Schwemmers, Sven, Gründer, Albert, Peeken, Jan C., Gothwal, Monika, Wehrle, Julius, Aumann, Konrad, Hamdi, Kamar, Dierks, Christine, Wang, Wei, Döhner, Konstanze, Jansen, Joop H., Pahl, Heike L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646501/
https://www.ncbi.nlm.nih.gov/pubmed/23589569
http://dx.doi.org/10.1084/jem.20120521