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The structure of the FANCM-MHF complex reveals physical features for functional assembly

Fanconi anemia (FA) is a rare genetic disease characterized by chromosomal instability and cancer susceptibility. The Fanconi anemia complementation group protein M (FANCM) forms an evolutionarily conserved DNA-processing complex with MHF1/MHF2 (histone-fold-containing proteins), which is essential...

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Detalles Bibliográficos
Autores principales: Tao, Yuyong, Jin, Changjiang, Li, Xu, Qi, Shali, Chu, Lingluo, Niu, Liwen, Yao, Xuebiao, Teng, Maikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646547/
https://www.ncbi.nlm.nih.gov/pubmed/22510687
http://dx.doi.org/10.1038/ncomms1779