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Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer

BACKGROUND: Malignant pleural effusion (MPE) is associated with advanced stages of lung cancer and is mainly dependent on invasion of the pleura and expression of vascular endothelial growth factor (VEGF) by cancer cells. As MPE indicates an incurable disease with limited palliative treatment option...

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Detalles Bibliográficos
Autores principales: Weibel, Stephanie, Hofmann, Elisabeth, Basse-Luesebrink, Thomas Christian, Donat, Ulrike, Seubert, Carolin, Adelfinger, Marion, Gnamlin, Prisca, Kober, Christina, Frentzen, Alexa, Gentschev, Ivaylo, Jakob, Peter Michael, Szalay, Aladar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646671/
https://www.ncbi.nlm.nih.gov/pubmed/23635329
http://dx.doi.org/10.1186/1479-5876-11-106