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Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity In Vivo
Monoclonal antibodies are widely used to target disease-related antigens. However, because conventional antibody binds to the antigen but cannot eliminate the antigen from plasma, and rather increases the plasma antigen concentration by reducing the clearance of the antigen, some clinically importan...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646756/ https://www.ncbi.nlm.nih.gov/pubmed/23667591 http://dx.doi.org/10.1371/journal.pone.0063236 |