The Second Intracellular Loop of the Human Cannabinoid CB2 Receptor Governs G Protein Coupling in Coordination with the Carboxyl Terminal Domain

The major effects of cannabinoids and endocannabinoids are mediated via two G protein-coupled receptors, CB1 and CB2, elucidation of the mechanism and structural determinants of the CB2 receptor coupling with G proteins will have a significant impact on drug discovery. In the present study, we syste...

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Detalles Bibliográficos
Autores principales: Zheng, Congxia, Chen, Linjie, Chen, Xiaopan, He, Xiaobai, Yang, Jingwen, Shi, Ying, Zhou, Naiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646771/
https://www.ncbi.nlm.nih.gov/pubmed/23667597
http://dx.doi.org/10.1371/journal.pone.0063262

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