Administration of Bleomycin via the Oropharyngeal Aspiration Route Leads to Sustained Lung Fibrosis in Mice and Rats as Quantified by UTE-MRI and Histology

Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes. In the present study, we investigated the oropharyngeal aspiration of bleomycin as an alternative route for the induction of lung fibrosi...

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Detalles Bibliográficos
Autores principales: Egger, Christine, Cannet, Catherine, Gérard, Christelle, Jarman, Elizabeth, Jarai, Gabor, Feige, Agnès, Suply, Thomas, Micard, Arthur, Dunbar, Andrew, Tigani, Bruno, Beckmann, Nicolau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646779/
https://www.ncbi.nlm.nih.gov/pubmed/23667616
http://dx.doi.org/10.1371/journal.pone.0063432

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